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. 2013 Mar-Apr;33(2):143–154. doi: 10.3747/pdi.2011.00033

Figure 6.

Figure 6

— Elimination rate of 3,4-dideoxyglucosone-3-ene (3,4-DGE) from the peritoneal cavity and appearance rate of 3,4-DGE in plasma. Mice were treated with phosphate buffered saline (PBS) or chlorhexidine gluconate (CG) 3 times in 1 week, and then 4 mL 3,4-DGE-containing PBS was injected into the peritoneal cavity. Peritoneal fluid was collected at 1, 10, 20, and 30 minutes after injection. (A) Residual concentration of 3,4-DGE in peritoneal fluid. Mice treated with CG showed rapid elimination of 3,4-DGE from the peritoneal cavity (PBS-treated: n = 8; CG-treated: n = 7). (B) Plasma level of 3,4-DGE in PBS- or CG-treated mice at 30 minutes after injection of 145 μmol/L 3,4-DGE. Compared with PBS-treated mice, those treated with CG showed high plasma levels of 3,4-DGE (PBS-treated: n = 2; CG-treated: n = 3). ** p < 0.01 versus PBS-treated mice.