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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: J Pediatr. 2012 Mar 16;161(2):270–5.e1. doi: 10.1016/j.jpeds.2012.02.007

Figure 3.

Figure 3

Biomarkers with an AUC value of 0.5 are no better than a coin flip in predicting the disease of interest. Those with an AUC value close to 1 have excellent positive predictive ability, whereas those with an AUC value close to 0 have excellent negative predictive ability. The reciprocal of a value will change a negative predictive value to a positive predictive value. This Figure shows the AUCs for Cys C, EGF, UMOD, and a combination of these 3 biomarkers. The model using all 3 biomarkers was not significantly different (AUC = 0.81) from the model with Cys C alone.