Table 1.
Diabetic patients (23) | Impaired glucose tolerance (27) | Normal glucose metabolism (17) | |
---|---|---|---|
Anthropometric characteristics | |||
Age, years |
56.95±10.38 |
49.76±9.04 |
42.56±7.49 |
p-0.671 | |||
M/F |
17/6 |
23/4 |
17/0 |
BMI, kg/m2 |
42.86±7.29 |
40.36±9.37 |
43.11±8.6 |
p-0.785 | |||
Waist circumference, cm |
133.2±20.84 |
130.12±15.96 |
138.14±19.76 |
p-0.421 | |||
Sleep study characteristics | |||
Mild to moderate OSA |
2/23(9%) |
11/27(40%) |
2/17 (12%) |
Severe OSA |
21/23 (91%) |
16/27 (60%) |
15/17 (88%) |
AHI, events/h |
58.79±34.25 |
53.00±35.33 |
62.33±30.58 |
p-0.671 | |||
Sleep duration, min |
194.03±56.81 |
192.87±55.04 |
236.41±59.11 |
p-0.09 | |||
Time with SpO2 <90%, |
70.85±25.99 |
56.03±33.44 |
49.75±32.4 |
p-0.114 | |||
Lipid profiles | |||
High density Chol, mmol/l |
1.27±0.31 |
1.27±0.35 |
1.29±0.26 |
p-0.982 | |||
Low density Chol, mmol/l |
2.86±0.07 |
3.03±0.093 |
3.24±1.03 |
p-0.448 | |||
Very low density Chol, mmol/l |
0.83±0.09 |
0.85±0.07 |
0.83±0.32 |
p-0.980 | |||
Tot Chol, mmol/l |
4.97±1.02 |
5.19±1.17 |
5.25±1.04 |
p-0.623 | |||
Trigl, mmol/l |
1.71±0.82 |
2.03±0.84 |
2.07±0.82 |
p-0.385 | |||
Insulin resistance | |||
Fasting glucose, mmol/l |
6.99 ±1.33 |
5.96±1.71 |
4.89 ±0.71 |
Immunoreactive insulin, mU/l |
18.92±16.57 |
31.06±28.05 |
22.65±12.45 |
p*-0.006 |
p**-0.229 |
p***-0.151 |
|
HOMA index |
4.86±4.46 |
7.48±7.66 |
5.24±3.33 |
p***-0.177 | |||
HbA1C |
6.69±1.11 |
6.41±1.06 |
5.63±0.44 |
p*-0.253 |
p**-0.003 |
p***-0.000 |
|
Biomarkers | |||
Resistin, ng/ml |
6.12±5.93 |
3.85±2.81 |
3.77±3.23 |
p*-0.021 |
p**-0.954 |
p***-0.043 |
|
Free fatty acids, mmol/l |
0.267±0.146 |
0.232±0.088 |
0.180±0.071 |
p*-0.78 |
p**-0.121 |
p***-0.037 |
|
Isoprostanes | 0.113±0.09 | 0.07±0.06 | 0.07±0.05 |
p-0.134 |
p- Kruskall –Wallis comparison between three groups; p*- Mann -Whithney comparison diabetics vs IGT; p**- Mann -Whithney comparison IGT vs NGM; p***- Mann -Whithney comparison diabetics vs NGM.