Table 2.
Distribution of apo E genotype frequencies in type 2 diabetic patients and non diabetic subjects
|
Variable |
T2DM (n=156) |
P Value |
Non diabetic subjects (n=155) |
P Value |
||
|---|---|---|---|---|---|---|
| WC normal (n=51) | WC abnormal (n=105) | WC normal (n=81) | WC abnormal (n=73) | |||
|
Sex (M/F) (n/%) |
29(18.6)/ 22(14.1) |
17(10.9)/ 88(56.4) |
<0.001* |
40(26)/ 41(26.6) |
14(9.1)/ 59(38.3) |
<0.001* |
|
Apo (E3/E3)/(E2/E3)/(E4/E3) (n/%) |
29(20.1)/5(3.5)/10(6.9) |
84(58.3)/11(7.6)/5(3.5) |
0.005* |
62(41.1)/11(7.3)/6(4) |
56(37.1)/11(7.3)/5(3.3) |
0.965 |
|
Age (yr) |
52 ± 12 |
51 ± 10 |
0.866 |
34 ± 10 |
46 ± 12 |
<0.001* |
|
BMI (kg/m2) |
25.4 ± 3 |
32 ± 5 |
<0.001* |
26 ± 4 |
33 ± 4 |
<0.001* |
|
SBP (mmHg) |
131 ± 20 |
143 ± 25 |
0.003* |
119 ± 22 |
135 ± 21 |
<0.001* |
|
DBP (mmHg) |
84 ± 13 |
90 ± 14 |
0.007* |
78 ± 13 |
88 ± 13 |
<0.001* |
|
FBS (mg/dl) |
125 ± 68 |
140 ± 67 |
0.175 |
75 ± 8 |
80 ± 10 |
0.002* |
|
TChol (mg/dl) |
199 ± 46 |
215 ± 48 |
0.042* |
188 ± 38 |
219 ± 42 |
<0.001* |
| £TG (mg/dl) | 241 ± 211 | 269 ± 197 | 0.029* | 135 ± 72 | 199 ± 133 | <0.001* |
Legend: T2DM: Type 2 Diabetes Mellitus, WC: Waist Circumference, waist circumference is >88 cm in women and >102 cm in men is defined as abnormal, M/F: Male/Female, BMI: Body Mass Index, SBP: Systolic Blood Pressure, DBP: Diastolic Blood Pressure, FBS: Fasting Blood Sugar, TChol: Total Cholesterol, TG: Triglyceride.
* P≤0.05 was considered as significant in statistical analysis, T- test.
£££Ê£ Analytic test was Mann–Whitney Test.