Table 3.
Major gene ontology biological process classifications represented by genes differentially expressed between control quarters from cows infected with S. aureus for 24 hours (SA24T0) and 72 hours (SA72T0)
| Clone accession no. | Gene symbol | gene | Fold Difference |
|---|---|---|---|
|
RESPONSE TO STRESS | |||
|
SA24T0 > SA72T0 |
|
|
|
|
CO891789 |
ASF1A |
ASF1 anti-silencing function 1 homolog A |
2.53 |
| pCXCL10* |
CXCL10 |
chemokine (C-X-C motif) ligand 10 |
3.28 |
|
AJ693004 |
CYP11A1 |
cytochrome P450, family 11, subfamily A, polypeptide 1 |
2.03 |
|
AM018876 |
FGA |
fibrinogen alpha chain |
2.03 |
| pIL1B* |
IL1B |
interleukin 1, beta |
2.72 |
|
AM037229 |
PENK |
proenkephalin |
2.23 |
|
BM256666 |
S100A8 |
S100 calcium binding protein A8 (calgranulin A) |
2.19 |
|
BF655078 |
S100A12 |
S100 calcium binding protein A12 (calgranulin C) |
2.29 |
|
AM031467 |
SOD2 |
superoxide dismutase 2, mitochondrial |
2.30 |
|
CO875497 |
TP53BP1 |
tumor protein p53 binding protein 1 |
2.68 |
|
AM022673 |
XRCC2 |
X-ray repair complementing defective repair in Chinese hamster cells 2 |
3.22 |
|
SA72T0 > SA24T0 |
|
|
|
|
CK847668 |
BRCA2 |
breast cancer 2, early onset |
3.47 |
|
CELL PROLIFERATION |
|
|
|
|
SA24T0 > SA72T0 |
|
|
|
|
AM009066 |
ACSL6 |
acyl-CoA synthetase long-chain family member 6 |
3.27 |
| pCXCL10* |
CXCL10 |
chemokine (C-X-C motif) ligand 10 |
3.28 |
|
CO874867 |
CSRP2 |
cysteine and glycine-rich protein 2 |
2.26 |
|
AM018876 |
FGA |
fibrinogen alpha chain |
2.03 |
| pIL1B* |
IL1B |
interleukin 1, beta |
2.72 |
|
AM024609 |
STIL |
SCL/TAL1 interrupting locus |
2.69 |
|
SA72T0 > SA24T0 |
|
|
|
|
CK847668 |
BRCA2 |
breast cancer 2, early onset |
3.47 |
|
BI680983 |
INHA |
inhibin, alpha |
2.63 |
|
AJ815547 |
IL7 |
interleukin 7 |
3.38 |
|
CELL DEVELOPMENT |
|
|
|
|
SA24T0 > SA72T0 |
|
|
|
|
AM009066 |
ACSL6 |
acyl-CoA synthetase long-chain family member 6 |
3.27 |
|
CO874867 |
CSRP2 |
cysteine and glycine-rich protein 2 |
2.26 |
|
BM256725 |
GZMH |
granzyme H |
2.35 |
| pIL1B* |
IL1B |
interleukin 1, beta |
2.72 |
|
CO887046 |
LRRC4C |
leucine rich repeat containing 4C |
2.46 |
|
AM031467 |
SOD2 |
superoxide dismutase 2, mitochondrial |
2.30 |
|
CO892784 |
ZEB2 |
zinc finger E-box binding homeobox 2 |
2.84 |
|
SA72T0 > SA24T0 |
|
|
|
|
AJ817391 |
AFF4 |
AF4/FMR2 family, member 4 |
3.20 |
|
CK847668 |
BRCA2 |
breast cancer 2, early onset |
3.47 |
|
BI680983 |
INHA |
inhibin, alpha |
2.63 |
|
AJ815547 |
IL7 |
interleukin 7 |
3.38 |
|
IMMUNE RESPONSE |
|
|
|
|
SA24T0 > SA72T0 |
|
|
|
|
AM011262 |
CTSG |
cathepsin G |
2.09 |
|
BF706666 |
CD4 |
CD4 molecule |
4.50 |
| pCXCL10* |
CXCL10 |
chemokine (C-X-C motif) ligand 10 |
3.28 |
| pFCGR3A* |
FCGR3A |
Fc fragment of IgG, low affinity IIIa, receptor (CD16) |
3.09 |
|
AM023116 |
GBP4 |
guanylate binding protein 4 |
2.16 |
| pIL1B* |
IL1B |
interleukin 1, beta |
2.72 |
|
AM011258 |
LTF |
lactotransferrin |
3.48 |
|
SA72T0 > SA24T0 |
|
|
|
|
AJ815547 |
IL7 |
interleukin 7 |
3.38 |
|
DEFENSE RESPONSE |
|
|
|
|
SA24T0 > SA72T0 |
|
|
|
| pCXCL10* |
CXCL10 |
chemokine (C-X-C motif) ligand 10 |
3.28 |
| pIL1B* |
IL1B |
interleukin 1, beta |
2.72 |
|
AM011258 |
LTF |
lactotransferrin |
3.48 |
|
AM037229 |
PENK |
proenkephalin |
2.23 |
|
BM256666 |
S100A8 |
S100 calcium binding protein A8 (calgranulin A) |
2.19 |
| BF655078 | S100A12 | S100 calcium binding protein A12 (calgranulin C) | 2.29 |
A single accession number is listed for genes represented by multiple clones. Average fold differences were calculated for superoxide dismutase 2, mitochondrial and lactotransferrin, which are represented by multiple clones. * pCXCL10, pFCGR3A and pIL1B are amplicons generated specifically for the Bov20K cDNA microarray.