Table 3.
Association of lipid associated SNPs with hypertension and diabetes related traits based on minor allele and within sib pair association estimates from the Fulker model
Gene | SNP | Hypertension | Systolic blood pressure | Diastolic blood pressure | Fasting glucose | Fasting insulin | BMI |
---|---|---|---|---|---|---|---|
APOA5 |
rs662799 |
0.84(0.65, 1.08), 0.18 |
−0.02(−0.09, 0.04), 0.51 |
−0.002(−0.07, 0.06), 0.12 |
−0.014(−0.08, 0.05), 0.67 |
0.04(−0.02, 0.11), 0.20 |
0.014(−0.05, 0.08), 0.63 |
APOB |
rs562338 |
0.79(0.58, 1.06), 0.12 |
−0.05(−0.13, 0.02), 0.17 |
−0.03(−0.11, -0.05), 0.45 |
−0.02(−0.10, 0.05), 0.53 |
0.01(−0.07, 0.09), 0.74 |
0.02(−0.05, 0.10), 0.49 |
CETP |
rs1864163 |
1.02(0.79, 1.31), 0.85 |
−0.03(−0.09, 0.03), 0.36 |
−0.03(−0.10, 0.03), 0.35 |
0.02(−0.04, 0.09), 0.49 |
0.009(−0.06, 0.08), 0.81 |
0.03(−0.03, 0.09), 0.40 |
GCKR |
rs780094 |
1.26(1.00, 1.59), 0.05 |
0.02(−0.04, 0.08), 0.46 |
0.04(−0.02, 0.10), 0.22 |
−0.01(−0.08, 0.05), 0.63 |
0.06( −0.003, 0.13), 0.06 |
−0.004(−0.06, 0.05), 0.88 |
LDLR |
rs6511720 |
1.88(1.23, 2.88), 0.003 |
0.06(−0.05, 0.17), 0.28 |
−0.01(−0.12, 0.10), 0.82 |
0.02(−0.09, 0.13), 0.73 |
−0.08(−0.19, 0.04), 0.19 |
−0.01(−0.11, 0.09), 0.84 |
LIPC |
rs4775041 |
0.98(0.78, 1.22), 0.83 |
−0.004(−0.07, 0.06), 0.9 |
−0.01(−0.08, 0.05), 0.65 |
−0.009(−0.07, 0.05), 0.79 |
0.03(−0.04, 0.09), 0.43 |
−0.02(−0.08, 0.03), 0.42 |
LPL | rs10503669 | 0.74(0.54, 1.02), 0.07 | −0.09(−0.17, -0.005), 0.04 | −0.04(−0.13, 0.04), 0.35 | −0.10(−0.18, -0.01), 0.02 | −0.11(−0.19, -0.02), 0.02 | −0.04(−0.12, 0.03), 0.28 |