Table 6.
Within sib pair association statistics for seven SNPs with lead lipid traits after stratifying for location
| Gene | Trait tested | Urban | Rural | Interaction effect |
|---|---|---|---|---|
|
APOA5 |
Triglycerides |
0.18 (0.09, 0.27, p=0.0001) |
0.19 (0.06, 0.32, p=0.004) |
−0.009 (−0.18, 0.16, p=0.91) |
|
APOB |
LDL-Cholesterol |
−0.04 (−0.20, 0.12, p=0.63) |
−0.11 (−0.22, -0.005, p=0.34 |
−0.06 (−0.26, 0.13, p=0.53) |
|
CETP |
HDL-Cholesterol |
−0.02 (−0.16, 0.22, p=0.78) |
−0.005 (−0.09, 0.08, p=0.90) |
0.04 (−0.13, 0.21, p=0.64) |
|
GCKR |
Triglycerides |
0.11 (0.03, 0.20, p=0.009) |
0.14 (0.01, 0.26, p=0.03) |
−0.004 (−0.16, 0.15, p=0.96) |
|
LDLR |
LDL-Cholesterol |
−0.05 (−0.20, 0.09, p=0.47) |
−0.13 (−0.36, 0.10, p=0.26) |
0.04 (−0.13, 0.21, p=0.64) |
|
LIPC |
HDL-Cholesterol |
0.05 (−0.04, 0.13, p=0.29) |
0.17 (0.04, 0.29, p=0.007) |
−0.11 (−0.27, 0.05, p=0.18) |
| LPL | Triglycerides | −0.21 (−0.32, -0.09, p=0.001) | −0.14 (−0.30, 0.02, p=0.09) | −0.07 (−0.28, 0.14, p=0.50) |
Data presented as β specific for z-scores with 95% CI and p-value.