Table 7.
Within sib pair association statistics for seven SNPs with lead lipid traits after stratifying for fat intake
| Gene | Trait tested | Low fat intake | Medium fat intake | Interaction effect |
|---|---|---|---|---|
|
APOA5 |
Triglycerides |
0.18 (0.08, 0.29, p=3.4 x 10-4) |
0.19 (0.08, 0.29, p=0.001) |
0.04 (−0.10, 0.19, p=0.55) |
|
APOB |
LDL-Cholesterol |
−0.11 (−0.23, 0.02, p=0.09) |
−0.07 (−0.18, 0.04, p=0.21) |
0.06 (−0.12, 0.23, p=0.53) |
|
CETP |
HDL-Cholesterol |
0.01 (−0.08, 0.11, p=0.78) |
−0.03 (−0.13, 0.07, p=0.61) |
−0.03 (−0.18, 0.11, p=0.63) |
|
GCKR |
Triglycerides |
0.11 (0.02, 0.21, p=0.02) |
0.13 (0.03, 0.23, p=0.01) |
−0.03 (−0.17, 0.11, p=0.69) |
|
LDLR |
LDL-Cholesterol |
0.02 (−0.15, 0.20, p=0.77) |
−0.20 (−0.36, -0.04, p=0.02) |
−0.03 (−0.18, 0.11, p=0.63) |
|
LIPC |
HDL-Cholesterol |
0.09 (−0.004, 0.18, p=0.06) |
0.09 (−0.004, 0.19, p=0.06) |
0.05 (−0.09, 0.19, p=0.48) |
| LPL | Triglycerides | −0.14 (−0.27, -0.004, p=0.04) | −0.21 (−0.34, -0.07, p=0.002) | −0.01 (−0.20, 0.17, p=0.87) |
Data presented as β specific for z-scores with 95% CI and p-value.