Table 2.

Effect of kolaviron, a biflavonoid fraction from Garcinia kola seeds, on urinary and blood biochemical indices in STZ-diabetic rats

Treatment
	Serum			Urine		Red cell
	Protein (mg/dL)	LDH (IU/L)	Glucose	Protein (mg/ 24h)	Creatinine (ml/min/ 100g)	HbA1c (%)
Normal	1.82 ± 0.46	501.8 ± 31.2	2.2 ± 0.4	0.7 ±0.06	0.62±0.09	4.2 ± 0.3
STZ only	1.63 ± 0.38	1007 ± 51.3*	8.6 ± 1.3*	3.4 ±0.5*	0.15±0.04*	8.3 ± 0.4*
STZ+KV	1.89 ± 0.50	613.2 ± 41.0**	3.2 ± 0.7**	1.3 ±0.07**	0.43±0.07**	5.0 ± 0.4**
STZ+GB	1.86 ± 0.44	998.5 ± 39.2*	2.7 ± 0.5**	1.1 ± 0.05**	0.37±0.05**	6.2 ± 0.2**

Values are means ± S.D. of 6 rats per group

^*Significantly different from normal at p< 0.05

^**Significantly different from STZ only at p< 0.05 STZ= Streptozotocin, KV= Kolaviron at 100 mg/kg, GB= Glibenclamide, HbA1c= Glycosylated hemoglobin, LDH= Lactate dehydrogenase