Table 1.
Baseline Characteristics by Aβ42/Aβ40 Tertile Among the 988 Older Adults
| Baseline Characteristics, M (SD) or n (%) | Low, n = 327 | Medium, n = 334 | High, n = 327 | p Value |
| Age, years | 74.1 (3.0) | 74.1 (2.7) | 73.8 (3.0) | .33 |
| Black (%) | 199 (60.9) | 169 (50.6) | 163 (49.9) | .007 |
| Female (%) | 186 (56.9) | 180 (53.9) | 179 (54.7) | .73 |
| Education ≥ high school (%) | 192 (58.7) | 224 (67.7) | 211 (64.5) | .05 |
| Depression (CES-D-10 score ≥ 10; %) | 12 (3.7) | 20 (6.0) | 19 (5.8) | .78 |
| 3MS score | 90.7 (5.4) | 91.4 (5.4) | 91.1 (5.4) | .25 |
| Stroke/TIA (%) | 33 (10.2) | 34 (10.4) | 28 (8.6) | .72 |
| Diabetes (%) | 93 (29.4) | 74 (22.8) | 68 (21.6) | .05 |
| Myocardial infarction (%) | 38 (11.7) | 32 (9.8) | 35 (10.9) | .73 |
| Hypertension (%) | 226 (69.1) | 219 (65.6) | 206 (63.0) | .25 |
| Body mass index (kg/m2) | 27.6 (4.6) | 27.7 (5.0) | 27.8 (5.2) | .79 |
| Cystatin C (mg/L, natural log) | 0.002 (0.3) | −0.01 (0.2) | −0.01 (0.3) | .67 |
| APOE e4 (%) | 118 (38.2) | 98 (31.1) | 70 (22.7) | <.001 |
Note: APOE = apolipoprotein; ECES-D = Center for Epidemiologic Studies-Depression Scale; TIA = transient ischemic attack.