Table 2.

The Adjusted^* Association Between Aβ42/Aβ40 and Depression Over Time, Stratified^† by APOE e4 Allele Status

N (%‡) With Depression Over 9 y and Adjusted Hazard Ratio (95% Confidence Interval)
	No e4 Allele		≥1 e4 Allele
Low (n = 315)	42 (13.3)	0.80 (0.52–1.23)	34 (10.8)	2.38 (1.15–4.92)
Medium (n = 314)	55 (17.5)	1.08 (0.73–1.61)	19 (6.1)	1.57 (0.71–3.47)
High (n = 308)	54 (17.5)	Ref	10 (3.2)	Ref

Notes: APOE = apolipoprotein E.

*Adjusted for race, education, diabetes, and baseline 3MS.

^† p Value for interaction = .003.

^‡Percentages shown are out of the total within in each tertile.