Figure 3.

Regional lung deposition of inhaled technetium-99m-labeled monodisperse albuterol aerosols. (A) 5 × 8 matrix was closely fitted to the krypton ventilation-scan lung boundary and superimposed on the posterior thorax aerosol deposition images, which was partitioned into a central zone, 2 × 3 matrix centered on the lung hilum; an intermediate zone, 3 × 5 matrix excluding the central zone; and a peripheral zone defined as the remaining lung field within the lung outline. (B) 1.5 μm, (C) 3 μm, and (D) 6 μm MMAD.

Note: Red areas indicate regions of highest radioactivity, and black of least radioactivity.

Reprinted with permission of the American Thoracic Society. Copyright © 2005 American Thoracic Society. Usmani OS, Biddiscombe MF, Barnes PJ. Regional lung deposition and bronchodilator response as a function of beta2-agonist particle size. Am J Respir Crit Care Med. 2005;172(12):1497–1504.²² Official journal of the American Thoracic Society.

Abbreviation: MMAD, mass median aerodynamic diameters.