Figure 7.

Inhibition of cell proliferation (Ki67) in 4T1 breast carcinoma tissue. The mice were treated as described in section 2.3 and tumor slides were immunostained with anti-Ki67. A) Control, B) Magh-citrate, C) Rh₂(H₂cit)₄D) Magh-Rh₂(H₂cit)₄. E) Quantification of Ki67 staining indicated that treatments with Rh₂(H₂cit)₄ and Magh-Rh₂(H₂cit)₄ inhibited tumor cell proliferation by nearly 50% within solid tumor sections when compared to untreated control mice. Data represent mean values ± standard error (n=4/each group) and different letters indicate statistical difference among treatments (p<0.05).