Formulation	Vesicle size (nm)	Polydispersity index	Zeta potential (mv)	Encapsulation efficiency (%)
P-LS/DOX	83.28	0.095	−26.2	95.8%
L-P-LS/DOX	89.56	0.17	−22.8	97.2%
S-P-LS/DOX	87.14	0.095	−22.3	96.3%
P-LS/FAM	98.04	0.302	−14.2	–
L-P-LS/FAM	95.50	0.163	−12.8	–
S-P-LS/FAM	97.25	0.207	−12.6	–
P-LS/DiR	80.84	0.186	−18.6	–
L-P-LS/DiR	82.66	0.202	−16.4	–
S-P-LS/DiR	85.36	0.179	−18.2	–

Note: Data are represented as mean values (n = 3).

Abbreviations: FAM, 5-carboxyfluorescein; DiR, 1,1′-dioctadecyl-3,3,3,3′ tetramethyl indotricarbocyanine iodide; DOX, doxorubicin; P-LS/DOX, PEG-liposomes loading DOX; L-P-LS/DOX, Lyp-1-PEG-liposomes loading DOX; S-P-LS/DOX, Syp-1-PEG-liposomes loading DOX; P-LS/FAM, PEG-liposomes loading FAM; L-P-LS/FAM, Lyp-1-PEG-liposomes loading FAM; S-P-LS/FAM, Syp-1-PEG-liposomes loading FAM; P-LS/DiR, PEG-liposomes loading DiR; L-P-LS/DiR, Lyp-1-PEG-liposomes loading DiR; S-P-LS/DiR, Syp-1-PEG-liposomes loading DiR; PEG, polyethylene glycol; SD, standard deviation.