Table 5.
Neurotransmitter levels and their metabolites (ng/g) after acute oral treatment with C. aurantium EO (5 mg/kg)
|
Structures and treatments | ||||||||
|---|---|---|---|---|---|---|---|---|
| |
Cortex |
Striatum |
Pons |
Hypothalamus |
||||
| TW | EO | TW | EO | TW | EO | TW | EO | |
| DA |
845.6 ± 239.9 (10) |
895.6 ± 321.3 (7) |
8324.3 ± 517.1 (11) |
8331.2 ± 1040.1 (7) |
15.2 ± 3.8 (10) |
18.6 ± 6.2 (7) |
53.1 ± 3.8 (10) |
58.3 ± 5.8 (6) |
| DOPAC |
94.6 ± 15.9 (12) |
85.6 ± 17.4 (8) |
437.4 ± 44.5 (11) |
415.5 ± 49.9 (7) |
11.6 ± 1.6 (11) |
8.4 ± 1.1 (8) |
58.6 ± 5.6 (12) |
64.2 ± 4.7 (8) |
| HVA |
427.3 ± 80.4 (12) |
567.8 ± 112.5 (8) |
1121.9 ± 96.8 (11) |
1384.9 ± 193.5 (7) |
317.2 ± 87.9 (11) |
388.3 ± 141.3 (8) |
236.2 ± 36.8 (12) |
388.8 ± 74.5 (8) |
| 5HT |
1246.9 ± 85.8 (12) |
1270.1 ± 81.0 (8) |
1686.3 ± 102.4 (11) |
1665.9 ± 170.9 (7) |
2782.4 ± 259.8 (11) |
2075.4 ± 309.9 (8) |
1660.1 ± 126.2 (12) |
1599.2 ± 113.9 (8) |
| 5HIAA | 192.7 ± 17.5 (12) | 229.3 ± 33.7 (8) | 317.1 ± 30.9 (11) | 320.3 ± 40.0 (7) | 879.2 ± 69.5 (10) | 644.1 ± 76.4 (7) | 341.7 ± 20.9 (12) | 310.9 ± 19.4 (8) |
TW (tween). The data are presented as the mean ± SEM. Any differences were compared with an unpaired t-test. The number of animals is different for each group because some structures could not be evaluated due to technical reasons.