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. 2013 Feb 22;18(1):4. doi: 10.1186/2047-783X-18-4

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Copyright ©2013 Zhuo et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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A case with membranous nephropathy (MN) and diabetic nephropathy (DN). (A) Deposits of mainly IgG collected in the basement membrane and appeared as a diffuse granular pattern as shown by immunofluorescence (IF, 200×). (B) Light microscopy showing membranous glomerulonephritis in which the capillary loops were thickened and prominent. Numerous granular dense deposits were located in subepithelial areas (PAS, 200×). (C) Thickened glomerular basement membrane (GBM) with numerous granular, dense deposits located in subepithelial areas (EM, 5000×). DN, diabetic nephropathy; GBM, glomerular basement membrane; IF, immunofluorescence; IgG, immunoglobulin G; MN, membranous nephropathy; PAS, periodic acid-Schiff.