Table 1.
Selected descriptive statistics for case subjects with head and neck squamous cell carcinoma and control subjects*
| Characteristic | Case subjects (n = 1056) |
Control subjects (n = 1252) |
p- value§ |
|---|---|---|---|
| Age (years) | |||
| Mean (SD) | 59.7 (11.4) | 60.8 (11.2) | |
| Sex | |||
| Male | 765 (72.4%) | 913 (72.9%) | |
| Female | 291 (28.6%) | 339 (27.1%) | |
| Race | |||
| White | 948 (90.0%) | 1119 (89.6%) | 0.09 |
| Other | 106 (10.0%) | 130 (10.4%) | |
| Education | |||
| High school diploma or Higher |
900 (87.1%) | 1134 (93.0%) | 0.002 |
| Did not finish high school | 133 (12.9%) | 85 (7.0%) | |
| Smoking, pack-years | |||
| None | 253 (24.0%) | 502 (40.1%) | <0.001 |
| >0 to <20 | 246 (23.3%) | 304 (24.3%) | |
| 20 to 45 | 272 (25.8%) | 264 (21.1%) | |
| ≥ 45 | 285 (27.0%) | 182 (14.5%) | |
| Alcohol consumption, average drinks per week |
|||
| <3 | 223 (21.2%) | 377 (30.2%) | 0.05 |
| 3 to <8 | 234 (22.2%) | 399 (31.9%) | |
| 8 to <25 | 276 (26.2%) | 315 (25.2%) | |
| ≥ 25 | 319 (30.3%) | 158 (12.7%) | |
| HPV 16 serology# | |||
| Negative | 318 (74.6%) | 517 (95.0%) | <0.001 |
| Positive | 108 (25.4%) | 27 (5.0%) |
*
SD = standard deviation, HPV16 = human papilloma virus type 16.
§
P-values using t-tests for categorical variables and ANOVA for continuous variables.
#
HPV serology only available for phase I subjects, E6 or E7 positive.