Figure 4. Plots of the creatinine concentration measured using either the Jaffe (closed circles) or the enzymatic assay (open triangles).
The dotted line shows the level of creatinine generally considered to be the upper level of the normal range (1.2 mg/dl). While all patients showed at least one elevated level when measured using the Jaffe method, creatinine measured using the enzymatic method was remarkably stable and consistently within the normal range. Mean (upper 95% CI) values of creatinine for the four patients in Figure 4 were 057(0.66), 0.65(0.77), 0.70(0.99), and 0.8(0.97) none of which show any evidence of impaired kidney function.