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. Author manuscript; available in PMC: 2013 Mar 15.
Published in final edited form as: Photodiagnosis Photodyn Ther. 2010 Aug 30;7(4):268–274. doi: 10.1016/j.pdpdt.2010.07.008

Table 1.

Elevated serum creatinine (Jaffe method) observed following 5-aminolevulinic acid (60 mg/kg)

Subject Light Dose
(J/cm2)3 		Creatinine 1 Maximum
mucositis
grade2
Baseline 1–2 h 4–5 h 24 h
1 50
continuous		 1.2 1.42 3
2 50
continuous		 0.87 0.82 3
3 50
continuous		 0.74 1.08 0.78 2
4 50
fractionated		 0.70 3.48 1.28 0.65 3
5 50
fractionated		 0.95 0.69 3.5 1.02 3
6 50
fractionated		 0.63 3.8 Not
available		 0.74 2
7 50
fractionated		 0.86 4.26 1.44 0.86 2
8 100
continous		 0.76 3.01 1.43 0.75 2
9 100
fractionated		 0.61 3.74 1.35 0.66 3
10 100
fractionated		 0.80 3.19 1.66 0.74 3
11 100
continous		 0.94 0.74 1.60 0.90 2
1

mg/dL (normal range: 0.64–1.27)

2

NCI Common Toxicity Criteria version 3.0 within the 4 weeks of follow-up evaluation.

3

Light dose was administered either continuously or interrupted for a time interval of 90–180 seconds.