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. Author manuscript; available in PMC: 2013 Mar 22.
Published in final edited form as: Nature. 2012 Mar 14;483(7390):428–433. doi: 10.1038/nature10892

Figure 3. NS1 suppresses antiviral gene transcription in infected cells.

Figure 3

a, Left: the GRO-seq profile of inducible RNA transcripts in uninfected (ui) A549 cells (black line) or cells infected with wild-type or ΔPAF virus (green and red lines, respectively). Right: GRO-seq profile of IFIT1 and IFI6 genes in uninfected and infected cells. b, GRO-seq profile of A549-expressed genes that are not affected by virus infection (left panel) or of the HPRT1 gene (right panel). Reads from either DNA strands are indicated as +/−. The y axes display reads per million mapped reads per 25 bp.