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. 2013 Mar 15;8(3):e59073. doi: 10.1371/journal.pone.0059073

Figure 6. IL-10 knock down inhibits the downregulatory effect of gp120 on Nef mediated IL-6 expression.

Figure 6

ELISA of IL-6 concentration in pg/ml was performed in immDCs treated with Nef, combination of Nef and gp120 and in the presence of IL-10 siRNA. Data represent the mean±SEM (n = 3). Statistical analysis was performed using Student's t-test, with the levels of significance defined as p*<0.05 and p**<0.01.