Table 2. Titers of RRV in thymus homogenates from infant BALB/c, NOD and C57BL/6 mice.
Day post infection | Proportion of thymuses in the given mouse strain from which a virus titer was obtained, and the virus titer | |||||
NOD | BALB/c | C57BL/6 | ||||
% of mice1 | Virus titer2 | % of mice | Virus titer | % of mice | Virus titer | |
1 | 25 (2/8) | 2,100 (340–13,000) | 75 (6/8) | 2,400 (380–11,000) | 71 (5/7) | 170 (17–3,200) |
2 | 75 (6/8) | 390 (100–1,500) | 22 (2/9) | 500 (190–1,300) | 0 (0/8) | NA3 |
3 | 38 (3/8) | 410 (68–1,200) | 17 (1/6) | 190 | 29 (2/7) | 880 (510–1,500) |
4 | 25 (2/8) | 110 (71–1,700) | 56 (5/9) | 3,500 (1,300–15,000) | 14 (1/7) | 1,500 |
5 | 0 (0/9) | NA | 17 (1/6) | 3,000 | 33 (2/6) | 260 (170–410) |
Percentage (no. giving a virus titer/no. collected) of mouse thymuses where an infectious virus titer could be determined. All organs where a titer was measurable also showed infectious virus by co-culture (Fig. 3).
Reciprocal geometric mean titer (range) of RRV in FCFU/thymus. No range is given when only a single thymus yielded a virus titer.
NA, not applicable. The infectious RRV level was below the limit of detection by titration.