Figure 4. Effects of IL-2 signaling on TGF-β-mediated regulation of T cell differentiation in B-cell NHL.

(A) Representative dot plots (n = 6) showing the expression of IFN-γ and IL-17 in CD4⁺ T cells treated with or without αIL-2 or αIL-2Rα or β in the presence or absence of TGF-β plus IL-6 and IL-23. (B) Representative dot plots (n = 3) showing the expression of Foxp3 and CD25 in CD4⁺ T cells treated with or without TGF-β, αIL-2 or αIL-2Rα or β alone or in combination. (C) Dot plots from a representative sample (n = 5) showing the expression of IFN-γ, IL-17 and IL-2 in CD4⁺ T cells treated with or without TGF-β or αIL-2.