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. 2013 Jan 9;12:10. doi: 10.1186/1475-2840-12-10

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Copyright ©2013 Hayashi et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Risk factors for IHD and CVA by Cox multivariate models in representative age groups (IHD, Left; CVA, Right). The upper panels show the analyses of IHD for those younger than 65 years old (Left) and CVA for those younger than 65 years old (Right). The lower panels show the analyses of IHD (Left) and CVA (Right) for those equal to or older than 75 years. HR stands for Hazard Ratio (vertical bar shows 1). Bold characters indicate statistically significant factors. The right side of each figure shows Hazard Ratios and 95% CIs. Because LDL-C/HDL-C interacts strongly with LDL-C and HDL-C and because non-HDL-C interacts with triglyceride and LDL-C, we analyzed non-HDL-C and LDL-C/HDL-C separately. In other words, common factors (gender, age, duration of diabetes, HbA1C, FPG, systolic BP (SBP), and diastolic BP (DBP)), TG, LDL-C and HDL-C were analyzed. Then, non-HDL-C and common factors were analyzed. Finally, LDL-C/HDL-C, common factors and TG were analyzed.