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. 2013 Feb 23;12:36. doi: 10.1186/1475-2840-12-36

Table 1.

Load-independent hemodynamic parameters

 
  
 Wild type
 Ob/ob
 DKO
  Condition Sham NP P Sham NP P Sham NP P
PRSW (mmHg)
 Untreated
 87.9±5.0
 60.2±11.8c
 76.3±5.4 cd
 64.5±2.5 a
 48.1±3.6 ac
 57.1±5.2 acd
 58.0±4.1 af
 48.6±6.5 ac
 49.2±3.0 acf
Diet
  
  
  
 65.8±1.7
 50.4±1.0 c
 64.4±3.1 bd
 58.2±3.0 f
 49.5±3.2 c
 55.9±3.5 bdf
ACE-I
 88.0±4.6
 59.3±6.8 c
 81.2±3.1 bcd
 72.4±3.1 abe
 52.3±3.6 ac
 69.8±2.9 abde
 65.9±5.3 abef
 51.1±3.6 ac
 63.9±3.3 abdef
Ees (mmHg/μl)
 Untreated
 8.3±2.5
 6.4±1.5
 8.5±1.7 d
 5.0±0.4 a
 4.8±1.7
 5.6±1.2 a
 6.0±2.2
 4.5±0.8 a
 4.8±2.3 a
Diet
  
  
  
 6.3±2.2
 4.4±1.2
 7.3±2.2d
 5.1±1.3
 5.4±1.2
 5.6±1.1
ACE-I
 6.0±1.1
 6.2±1.6
 8.7±1.7 cd
 5.3±1.7
 4.2±1.3
 6.4±1.6 ad
 5.6±1.4
 4.3±1.4
 5.2±3.0 a
EDPVR (mmHg/μl) Untreated
 0.2±0.2
 0.4±0.2
 0.3±0.2
 0.4±0.3
 0.4±0.3
 0.5±0.3 a
 0.5±0.4
 0.3±0.1
 0.3±0.2
Diet
  
  
  
 0.3±0.2
 0.2±0.1
 0.2±0.1 b
 0.3±0.1
 0.2±0.1 b
 0.3±0.2
ACE-I 0.2±0.2 0.4±0.4 0.2±0.1 0.4±0.1 0.3±0.1 0.3±0.1 bc 0.3±0.1 f 0.3±0.1 0.2±0.1

ACE-I: angiotensin-converting enzyme inhibition; DKO: double knock-out (ob/ob; LDLR-/-); EDPVR: end-diastolic pressure-volume relationship; Ees: end-systolic elastance; IR: ischemia/reperfusion; NP: Non-Preconditioned and ischemia/reperfusion; P: Preconditioned and ischemia/reperfusion; PRSW: preload recruitable stroke work; sham: group without ischemia/reperfusion. “a” p<0.05 versus WT same treatment, same condition (sham; non-preconditioned; preconditioned); “b” p<0.05 versus same untreated genotype, same condition; “c” p<0.05 versus sham, same genotype, same treatment; “d” p<0.05 versus non-preconditioned, same genotype, same treatment; “e” p<0.05 versus diet, same genotype, same condition; “f” p<0.05 versus ob/ob same treatment, same condition.