Table 2.
Variants in virulence related genes
| Gene | Gene ID | Position | Ref base | Alt base | Substitution | Invasive | SSTI |
|---|---|---|---|---|---|---|---|
| immunoglobulin G binding protein A precursor |
SAUSA300_0113 |
128554 |
G |
T |
N380K |
0 |
1 |
| IucC family siderophore biosynthesis protein |
SAUSA300_0123 |
142320 |
G |
T |
S404I |
1 |
0 |
| sucrose-specific PTS tranporter protein |
SAUSA300_0194 |
226384 |
C |
T |
A153V |
1 |
0 |
| sucrose-specific PTS tranporter protein |
SAUSA300_0194 |
226642 |
G |
A |
G239D |
0 |
1 |
| choloylglycine hydrolase family protein |
SAUSA300_0269 |
321604 |
C |
A |
P194T |
0 |
1 |
| essC protein |
SAUSA300_0283 |
336391 |
G |
A |
E142K |
0 |
1 |
| essC protein |
SAUSA300_0283 |
336694 |
A |
G |
I243V |
1 |
0 |
| superantigen-like protein 5 |
SAUSA300_0399 |
451121 |
C |
A |
A7E |
1 |
1 |
| superantigen-like protein |
SAUSA300_0407 |
460962 |
TACAG |
----- |
Frameshift 108 |
11 |
10 |
| dimethyladenosine transferase |
SAUSA300_0470 |
530052 |
T |
A |
V258E |
0 |
1 |
| clumping factor A |
SAUSA300_0772 |
859497 |
C |
A |
A117D |
0 |
1 |
| enterotoxin Q |
SAUSA300_0801 |
884359 |
T |
- |
Frameshift 142 |
1 |
0 |
| cysteine protease precursor |
SAUSA300_0950 |
1038844 |
A |
T |
V206E |
0 |
1 |
| fmt protein |
SAUSA300_0959 |
1051797 |
C |
T |
T269I |
0 |
1 |
| alpha-hemolysin precursor |
SAUSA300_1058 |
1157169 |
G |
T |
T53N |
0 |
1 |
| putative fibronectin/fibrinogen binding protein |
SAUSA300_1101 |
1204860 |
C |
A |
D555Y |
0 |
2 |
| putative enterotoxin type A |
SAUSA300_1559 |
1708640 |
C |
A |
E78* |
1 |
0 |
| cell wall surface anchor family protein |
SAUSA300_1702 |
1878567 |
G |
A |
P1968S |
1 |
0 |
| cell wall surface anchor family protein |
SAUSA300_1702 |
1878783 |
G |
C |
Q1896E |
0 |
1 |
| cell wall surface anchor family protein |
SAUSA300_1702 |
1878930 |
C |
A |
A1847S |
0 |
1 |
| cell wall surface anchor family protein |
SAUSA300_1702 |
1880436 |
C |
T |
E1345K |
0 |
1 |
| cell wall surface anchor family protein |
SAUSA300_1702 |
1880783 |
G |
A |
A1229V |
0 |
1 |
| serine protease SplA |
SAUSA300_1758 |
1943333 |
T |
C |
D113G |
0 |
1 |
| lantibiotic epidermin biosynthesis protein EpiC |
SAUSA300_1765 |
1950378 |
A |
G |
V209A |
0 |
1 |
| lantibiotic epidermin biosynthesis protein EpiB |
SAUSA300_1766 |
1953206 |
T |
- |
Frameshift 261 |
0 |
1 |
| leukotoxin LukD |
SAUSA300_1768 |
1955543 |
C |
T |
V254I |
1 |
0 |
| leukotoxin LukE |
SAUSA300_1769 |
1957230 |
T |
C |
K4E |
0 |
1 |
| Aerolysin/leukocidin family protein |
SAUSA300_1975 |
2130674 |
G |
A |
A63V |
1 |
0 |
| Aerolysin/leukocidin family protein |
SAUSA300_1975 |
2130847 |
T |
- |
Frameshift 5 |
0 |
1 |
| hyaluronate lyase precursor |
SAUSA300_2161 |
2338286 |
G |
T |
K65N |
0 |
1 |
| hyaluronate lyase precursor |
SAUSA300_2161 |
2340008 |
A |
T |
L639F |
1 |
0 |
| AcrB/AcrD/AcrF family protein |
SAUSA300_2213 |
2380381 |
- |
T |
Frameshift 1050 |
0 |
1 |
| AcrB/AcrD/AcrF family protein |
SAUSA300_2213 |
2382879 |
A |
T |
L218* |
0 |
1 |
| teicoplanin resistance associated membrane protein TcaB protein |
SAUSA300_2301 |
2473522 |
C |
G |
W311C |
0 |
1 |
| IgG-binding protein SBI |
SAUSA300_2364 |
2540728 |
G |
A |
E150K |
0 |
1 |
| IgG-binding protein SBI |
SAUSA300_2364 |
2540773 |
C |
A |
Q165K |
1 |
0 |
| IgG-binding protein SBI |
SAUSA300_2364 |
2540911 |
G |
A |
V211M |
1 |
1 |
| gamma-hemolysin component A |
SAUSA300_2365 |
2542364 |
C |
A |
Q80K |
1 |
0 |
| gamma-hemolysin component C |
SAUSA300_2366 |
2543638 |
A |
G |
I6V |
0 |
1 |
| putative transporter |
SAUSA300_2406 |
2591556 |
A |
C |
M273R |
2 |
0 |
| clumping factor B | SAUSA300_2565 | 2774393 | C | T | G883R | 0 | 1 |