Table 2.
Increased Treg cell frequency is associated with ICS use and not asthma disease Severity
| Patient Classification | n | % Treg cells/CD4+ cells (mean, adjusted) | effect* | 95%CI | p- value |
|---|---|---|---|---|---|
| Children not on ICS |
119 |
6.32 |
-- |
-- |
0.02 |
| Children treated with ICS |
40 |
7.37 |
1.06 |
(0.15, 1.96) |
|
| No asthma |
93 |
6.93 |
-- |
-- |
0.96 |
| Intermittent |
31 |
6.77 |
-0.17 |
(-0.91, 0.57) |
|
| Mild persistent |
15 |
6.77 |
-0.17 |
(-1.15, 0.82) |
|
| Mod/Sev persistent |
20 |
6.91 |
-0.02 |
(-1.17, 1.12) |
|
| Interaction: P = 0.78 | |||||
ICS Inhaled corticosteroid, 95% CI, 95% confidence interval.
*differences in least squares (LS) means in%Treg cells/CD4+ cells between the groups.