Table 4.
Increased Treg Cell Frequency is Associated with ICS Use and Not Asthma Status
| Patient Classification | n | %Treg cells/CD4+ cells (mean, adjusted) | effect* | 95%CI | p-value |
|---|---|---|---|---|---|
| Children not on ICS |
118 |
6.30 |
-- |
-- |
0.005 |
| Children treated with ICS |
39 |
7.55 |
1.26 |
(0.40, 2.12) |
|
| No asthma |
93 |
7.03 |
-- |
-- |
0.68 |
| Non-atopic asthma |
20 |
7.05 |
0.02 |
(-0.80, 0.84) |
|
| Atopic asthma |
44 |
6.69 |
-0.34 |
(-1.18, 0.50) |
|
| Interaction: P = 0.35 | |||||
ICS Inhaled corticosteroid, 95% CI, 95% confidence interval.
*difference in LS means%Treg cells/CD4+ cells between the groups. Two asthma subjects are missing FEIA data and were excluded from the analysis.