Skip to main content
. 2013 Mar 15;8(3):e58717. doi: 10.1371/journal.pone.0058717

Table 1. Means and standard deviations of BMI for each polymorphism, and main effects and post hoc comparisons of SNPs that showed significant main effects and were used in subsequent multiple regression analysis.

SNP Subsystem Gene Maj Mean SD n Het Mean SD n Min Mean SD n F p mh mm hma Gene bygenderinteractionF(p)
rs6651806 Degradation MAOB AA 20.63 2.45 381 AC 19.95 2.16 97 CC 6.32 0.01 b 0.40 (0.53)
rs5905512 MAOB AA 20.76 2.62 284 AG 20.10 2.01 194 GG 9.02 <0.01 b 0.02 (0.89)
rs1018079 Transport SLC18A1 AA 20.29 2.26 303 AG 20.72 2.32 156 GG 22.10 4.35 18 5.92 <0.01 0.07 <0.01 0.02 0.34 (0.71)
rs2270638 SLC18A1 AA 20.33 2.47 344 AG 20.92 2.20 133 GG 5.77 0.02 b 0.27 (0.60)
rs977003 Receptor HTR2A AA 20.29 2.30 299 AC 20.92 2.62 151 CC 20.40 2.19 28 3.45 0.03 0.01 0.82 0.29 0.14 (0.87)
rs2224721 HTR2A CC 20.12 2.12 216 AC 20.79 2.61 209 AA 20.87 2.51 53 4.85 0.01 <0.01 0.04 0.82 0.13 (0.88)
rs2192371 HTR2C AA 20.61 2.42 242 AG 19.79 1.80 124 GG 21.03 2.78 112 8.62 <0.01 <0.01 0.12 <0.01 0.95 (0.33)
rs6644065 HTR2C AA 20.45 2.26 373 AG 20.05 2.81 68 GG 21.74 2.77 37 6.30 <0.01 0.21 <0.01 <0.01 6.06 (0.01)
rs4911871 HTR2C AA 20.39 2.23 350 AG 20.17 2.74 76 GG 21.68 2.76 51 7.44 <0.01 0.47 <0.01 <0.01 1.09 (0.30)
rs11214769 HTR3B AA 20.31 2.22 335 AG 20.88 2.85 124 GG 21.21 2.20 19 3.46 0.03 0.02 0.11 0.58 1.65 (0.19)
rs13166761 HTR4 GG 20.38 2.23 244 AG 20.79 2.64 202 AA 19.48 1.81 32 4.74 0.01 0.07 0.05 <0.01 0.54 (0.59)
rs7904569 HTR7 AA 20.50 2.38 206 AG 20.69 2.53 215 GG 19.72 1.85 57 3.64 0.03 0.43 0.03 0.01 1.34 (0.26)

Note: Empty cells mean no such genotypes were found in our sample. Maj: Major allele; Het: Heterozygote; Min: Minor allele.

a

Results (p values) of post hoc comparisons. mh = Maj versus Het, mm = Maj versus Min, hm = Het versus Min.

b

Post hoc comparison was not run because there were only 2 groups for this locus.