Table 3. 1H chemical shift assignments for Htel (δ) in the presence of 1 and 2a.
TTAGGG/1 | NH | H2/H8/H6 | H1′ | H2′,H2′′ | H3′ | H4′ | CH3 |
T1 | − | 7.43 | 6.05 | 2.42, 2.11 | 4.86 | 4.11 | 1.86 |
T2 | − | 7.43 | 6.05 | 2.42, 2.18 | 4.86 | 4.24 | 1.86 |
A3 | − | 8.10,8.51 | 6.38 | 2.98, 2.98 | 5.19 | 4.57 | − |
G4 | 11.23 | 7.72 | 6.07 | 2.93, 2.60 | 5.04 | 4.32 | − |
G5 | 10.89 | 7.48 | 6.07 | 2.91, 2.68 | 5.03 | 4.39 | − |
G6 | 10.53 | 7.37 | 6.12 | 2.87, 2.66 | 4.88 | 4.53 | − |
TTAGGG/2 | NH | H2/H8/H6 | H1′ | H2′,H2′′ | H3′ | H4′ | CH3 |
T1 | − | 7.60 | 6.06 | 2.48,2.28 | 4.85 | 3.96 | 1.93 |
T2 | − | 7.46 | 6.23 | 2.49, 2.25 | 4.93 | 4.28 | 1.93 |
A3 | − | 8.10,8.54 | 6.42 | 3.02, 3.02 | 5.22 | 4.61 | − |
G4 | 11.35 | 7.88 | 6.11 | 3.02, 2.76 | 5.03 | 4.43 | − |
G5 | 10.96 | 7.59 | 6.20 | 3.02,2.83 | 5.17 | 4.46 | − |
G6 | 10.61 | 7.46 | 6.23 | 3.00, 2.77 | 4.96 | 4.62 | − |
Measured in ppm at 25°C, R = [drug]/[DNA] = 3.0.