Table 4. Inter-molecular NOE interactions between protons of the 1 with protons of Htel^a.

TTAGGG	1	Theoretical distances(Å)
CH3 T2	H1 or H4	4.31 (H4)
H2′ A3	H1 or H4	4.37 (H4)
H2′ A3	H2 or H3	4.33 (H3)
H1′ A3	H2 or H3	1.68 (H3)
H3′, G4 or A3	H3A	3.96 (A3)

The distances are calculated on the basis of the 1 best docked conformation.

^aAcquired at 25°C, R = [drug]/[DNA] = 3. 2′ H and 2″ H stand for low field and up field proton respectively.