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HCC cell lines and caveolin-1 expression. (A) HUH-7, Hep3B and PLC/PRF/5 are weak caveolin-1 expressing cells (both on mRNA and protein level, qPCR data normalized to 18S rRNA), whereas the dedifferentiated lines HLE, HLF and FLC-4 demonstrate high expression levels. (B) Based on elevated basal migration capacity, assessed with the transwell assay, HLE, HLF and FLC-4 are considered dedifferentiated (see text for details).
