Table 2.
Structural neuroimaging findings in panic disorder [diffusion tensor imaging]
| Study | Subjects | No.of subjects(female) | Mean age(SD) | Clinical state | Duration of illness(years) | Comorbid Depression | Comorbid Agoraphobia | Medication status | Field strength(Tesla) | Slice thickness(mm) | Amygdala | Hippocampus | Ventromedial Prefrontal cortex | Other brain regions |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Han, 2008 [23] |
PD |
24 (10) |
31.9 (6.8) |
PDSS 9.5 (6.4) |
3.6 (1.9) |
HDRS-17 scores of PD patients were not different from those of HC subjects. |
Not mentioned |
Combination of antidepressants and anxiolytics |
3.0 |
3.5 |
Not assessed |
Not assessed |
Left anterior cingulate, right posterior cingulate FA value▲ |
Not assessed |
| HC | 24 (10) | 30.6 (5.1) | - | - | - | - |
Abbreviations: FA, fractional anisotropy; HC, healthy control; PD, panic disorder; PDSS, Panic Disorder Severity Scale; SD, standard deviation.