Table 3.
List of transcription factors having over-representative occurrence in brain specific cis-acting sites
| Transcription factor | Protein-related information | Known endogenous expression pattern | Source |
|---|---|---|---|
| AML1 |
RUNT-type transcription factor |
spinal cord, hindbrain |
[29,30] |
| ARNT |
Helix-loop-helix DNA-binding |
spinal cord, forebrain, midbrain, hindbrain |
[31,32] |
| cFOS |
Basic-leucine zipper (bZIP) transcription factor |
hindbrain |
[33,34] |
| c-REL |
Immunoglobulin-like fold |
CNS (components not defined yet) |
[35,36] |
| FREAC |
Winged helix-turn-helix transcription repressor |
CNS (components not defined yet) |
[37,38] |
| HFH |
Winged helix-turn-helix transcription repressor DNA |
CNS (components not defined yet) |
[39,40] |
| HNF3B |
Winged helix-turn-helix transcription repressor DNA |
Spinal-cord, forebrain midbrain, hindbrain |
[41,42] |
| MEF2 |
myocyte-specific enhancer factor 2A |
forebrain, hindbrain |
[43,44] |
| NF-KappaB |
Immunoglobulin-like fold |
spinal cord, forebrain, midbrain, hindbrain |
[45,46] |
| nMYC |
Helix-loop-helix DNA-binding |
spinal cord, forebrain, midbrain, hindbrain |
[47,48] |
| SOX17 |
High mobility group, HMG1/HMG2 |
spinal cord, forebrain, midbrain, hindbrain |
[49] |
| SOX5 |
High mobility group, HMG1/HMG2 |
spinal cord, hindbrain, midbrain |
[50,51] |
| Talbeta-E47S |
Helix-loop-helix DNA-binding |
spinal cord, forebrain, midbrain, hindbrain |
[52,53] |
| USF | Helix-loop-helix DNA-binding | spinal cord, forebrain, hindbrain | [38,54] |
This table also provides references of literature (last column) that addresses the type/function and endogenous expression pattern of transcription factors.