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Combination of ABT-737 and chloroquine does not result in increased efficacy in xenografts models. Tumor bearing Nu/Nu mice (4–7 per treatment arm) were treated daily with ABT-737 (100 mg/kg, IP),CQ (60 mg/kg, IP), combination, or an equal amount of vehicle control for 18–21 days. Tumor volumes were measured every three days. Group means and standard error of the mean for each measurement are shown.
