Table 4.

Univariable and multivariable Cox regression analysis for disease-free survival

	Univariable		Multivariable
	p-value	HR (95% CI)	p-value	HR (95% CI)
Tumor location	0.105	1.628 (0.898 – 2.822)	0.065	0.557 (0.310 – 1.038)
pG	0.046		0.031
1		0.597 (0.229 – 1.848)		0.431 (0.158 – 1.372)
2		1.207 (0.522 – 3.504)		0.899 (0.377 – 2.658)
3		2.023 (1.155 – 3.724)		2.089 (1.184 – 3.872)
TNM stage	0.004	3.454 (1.543 – 6.979)	0.013	2.978 (1.313 – 6.123)
≥4 genes or/and TGF-β1	0.033	1.903 (1.053 – 3.530)	0.041	1.885 (1.025 – 3.559)

HR (95% CI) hazard ration with 95% confidence interval, pG tumor differentiation.