Table 2.
The associaition of MACC1 mRNA expression with the baseline clinical presentation in advanced HCC patients
| Variables | All cases (n = 120 ) | MACC1 mRNA high expression (total cases = 60) [n(%)] | MACC1 mRNA low expression (total cases = 60) [n(%)] | P value |
|---|---|---|---|---|
|
Gender | ||||
| Male |
106 |
52(87) |
54(90) |
0.7761 |
|
Age |
|
|
|
|
| ≥ 48 years |
60 |
25(42) |
38(63) |
0.0283 |
|
Tumor size |
|
|
|
|
| ≥ 6 cm |
60 |
37(62) |
18(30) |
0.0010 |
| HCC thrombus |
|
|
|
|
| Portal trunk |
49 |
32(53) |
17(28) |
0.0093 |
|
HCC number |
|
|
|
|
| Multinodular |
53 |
32(53) |
21(35) |
0.0432 |
|
Differentiation |
|
|
|
|
| Well |
20 |
8(13) |
12(20) |
0.0347 |
| Moderately |
50 |
20(34) |
30(50) |
|
| Poorly |
50 |
32(53) |
18(30) |
|
|
Serum AFP |
|
|
|
|
| ≥1368 |
85 |
41(68) |
44(73) |
0.6879 |
|
HBV DNA |
|
|
|
|
| Positive |
76 |
36(60) |
40(67) |
0.4486 |
|
Child-Pugh |
|
|
|
|
| A |
58 |
31(52) |
27(45) |
0.4650 |
| B | 62 | 29(48) | 33(55) | |