Table 2.
Presenting symptoms of all 124 eligible children
| Symptom | Number of patients (%) | |
|---|---|---|
|
Gastrointestinal tract |
|
|
| |
Vomiting |
30 (24.2%) |
| |
Diarrhea |
17 (13.7%) |
| |
Constipation |
14 (11.3%) |
| |
Colic |
24 (19.4%) |
| |
Bloody stool |
17 (13.7%) |
| |
Abdominal pain |
3 (2.4%) |
| |
Feeding problems |
15 (12.1%)† |
|
Respiratory tract |
|
|
| |
Dyspnea and wheezing |
13 (10.5%) |
|
Skin manifestations |
|
|
| |
Eczema |
50 (40.3%) |
| |
Swelling |
5 (4.0%)‡ |
| |
Urticaria |
3 (2.4%) |
| |
Erythematous exanthema |
10 (8.1%) |
|
Other |
|
|
| |
Excessive crying |
59 (47.6%) |
| Positive family history | 8 (6.5%)* | |
† Feeding problems were significantly more often present in the DBPCFC-negative group (p=0.046).
‡ Swelling was significantly more often present in the DBPCFC-positive group (p=0.023).
*In these 8 children the positive family history was one of the reasons for performing the double-blind placebo-controlled food challenge. In total 65 children (52.4%) had a positive family history.