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H2O2-scavenging enzymes in WT and Tg hippocampus. (a, c) Densitometric values of CAT and GPX1 WB performed on hippocampal protein extracts of 3-, 6-, 9-, 12-, and 18-month-old WT and Tg brains. Values are expressed as mean ± SD. *P <0.05; **P <0.01; ***P <0.001. (b, d) CAT and GPX1 immunolocalization in CA1 hippocampal field of 3-, 6-, 9- and 18-month-old WT and Tg brains. or, stratum oriens; pyr, stratum pyramidale; rad, stratum radiatum. Scale bars, 25 μm.
