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. 2013 Feb 2;8:8. doi: 10.1186/1750-1326-8-8

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Copyright ©2013 Fanelli et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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SOD2 protein levels and distribution in WT and Tg hippocampus. (a) Densitometric values of SOD2 WB performed on hippocampal protein extracts of 3-, 6-, 9-, 12- and 18-month-old WT and Tg brains. Values are expressed as mean ± SD. **P <0.01; ***P <0.001. (b) SOD2 immunolocalization in CA1 hippocampal field of 3-, 6-, 9-, 12- and 18-month-old WT and Tg brains. or, stratum oriens; pyr, stratum pyramidale; rad, stratum radiatum. Scale bars, 25 μm. (c) Higher magnification showing SOD2 immunopositive glial cells around senile plaques in 18-month-old Tg hippocampus. Scale bar, 15 μm.