Figure 1.

Relationship between temperature and the development rate of P. vivax. The function as proposed by Brière et al.[30] is fitted to a set of empirical data (see Methods for references) and the well-established Detinova equation [37] over a defined temperature range (black line). The previously published thermal performance curve for P. falciparum is plotted in grey. The optimal temperature for P. falciparum development in this curve is 30.1°C and 29.4°C for P. vivax.