Table 5.
Cost, incremental cost and impact of screening strategies
| |
Targeted screening |
Universal |
|||
|---|---|---|---|---|---|
| ≥ age 50† | ≥ age 45 | ≥ age 40 | ≥ age 35 | screening | |
|
Overall |
|
|
|
|
|
| Estimated cost to detect 1 high risk individual, MYR (USD) |
92.64 (29.73) |
110.08 (35.33) |
131.51 (42.20) |
158.13 (50.75) |
187.2 (60.08) |
| Incremental cost per additional high risk individual detected, MYR |
- |
490.27 |
2060.12 |
15483.29 |
358444.85 |
| (USD) |
- |
(157.34) |
(661.14) |
(4968.96) |
(115033.65) |
| NNS to prevent one CV event |
62.24 |
76.14 |
96.64 |
123.95 |
146.73 |
| NNS to prevent one CV event (sensitivity analyses) |
168.47 |
206.07 |
261.57 |
335.48 |
397.15 |
|
Males |
|
|
|
|
|
| Estimated cost to detect 1 high risk individual, MYR (USD) |
69.05 (22.16) |
82.64 (26.52) |
99.44 (31.91) |
121.01 (38.84) |
144.13 (46.25) |
| Incremental cost per additional high risk individual detected, MYR |
- |
306.21 |
1180.58 |
8825.99 |
258952.77 |
| (USD) |
- |
(98.27) |
(378.88) |
(2832.47) |
(83104.23) |
| NNS to prevent one CV event |
45.33 |
57.27 |
72.96 |
94.33 |
112.36 |
| NNS to prevent one CV event (sensitivity analyses) |
120.13 |
151.77 |
193.36 |
249.97 |
297.77 |
|
Females |
|
|
|
|
|
| Estimated cost to detect 1 high risk individual, MYR (USD) |
133.01 (42.69) |
158.88 (50.99) |
189.18 (60.71) |
225.02 (72.21) |
264.83 (84.99) |
| Incremental cost per additional high risk individual detected, MYR |
- |
1426.50 |
8669.32 |
76295.96 |
293818.47 |
| (USD) |
- |
(457.8) |
(2782.19) |
(24485.23) |
(94293.47) |
| NNS to prevent one CV event |
85.72 |
105.59 |
129.78 |
165.01 |
194.20 |
| NNS to prevent one CV event (sensitivity analyses) | 240.97 | 394.25 | 364.83 | 463.95 | 545.95 |
CV cardiovascular, NNS numbers needed to screen.
MYR Malaysian Ringgit, USD US Dollar. 1.00 USD = 3.11600 MYR.
* for incremental costs, reference screening strategy is directly to the left of screening strategy assessed.
† first reference group (for ages ≥ 45).