Figure 3.

In vivo pulmonary inflammatory indices. Inflammatory chemokines, monocyte chemotactic protein (MCP)-1 (A) and macrophage inflammatory protein (MIP)-2 (B), were measured in the acellular BALF recovered from rats 1, 3, 5, 7, 14, and 28 days after intratracheal-instillation with 1.25, 5.0, or 12.5 μg of QD-NH₂ or QD-COOH. * significantly different from all groups; ⁺ significantly different from saline, 1.25 μg, and 5.0 μg groups; ^# significantly different from saline and 1.25 μg groups; ^@ significantly different from saline, 1.25 μg groups, and QD-NH₂ at 5.0 μg; ^~ significantly different from 12.5 μg dose, 1.25 μg dose, and saline; ^ significantly different from saline (p<0.05).