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. 2012 Nov 21;2:20. doi: 10.1186/2043-9113-2-20

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Copyright ©2012 Crooke et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Discrimination of IBD from CTRL and IBS from CTRL using the ratioscore system. (A) Ability of a single ratio, PGK1/POU6F1, to discriminate IBD and CTRL subjects. (B) The most discriminatory 25 gene-expression ratios were identified to segregate IBD and CTRL subjects. The ratioscore method was applied to combine ratio performance into a single discriminator. (C) Ability of a single ratio, PGK1/POU6F1, to discriminate IBS and CTRL subjects. (D) The most discriminatory 19 gene-expression ratios were identified to segregate IBS and CTRL subjects. The ratioscore method was applied to combine ratio performance into a single discriminator * indicates ratios found in both IBD:CTRL and IBS:CTRL comparisons.