Figure 1. The Hot Dog Fold.
(A) E. coli dehydratase–isomerase (Fab A, PDB#1MKA) in green with the hot dog helix (αHD) viewed head-on and colored purple. A “bun” of β-sheet wraps around αHD. (B) FabA rotated around the x axis 90° to look down on the length of the “hot dog”.