Table 1.

Diffusion rates of CD81, SR-BI and HCVpp in different cells assessed by FRAP and SPT

Methodology	Cell	Track	Diffusion coefficient (DC), μm2 s−1						Significanceb
			Polarized			Non-polarized
			Median	IQR	na	Median	IQR	n
FRAP	HepG2	CD81	0.07	0.13	250	0.11	0.24	250	***
		SR-BI	0.16	0.24	250	0.14	0.36	250
	Huh-7.5	CD81	–	–	–	0.09	0.15	250
		SR-BI	–	–	–	0.13	0.58	250
	Huh-6	CD81	–	–	–	0.12	0.29	250
		SR-BI	–	–	–	0.15	0.29	250
	PHH	CD81	–	–	–	0.10	0.21	250
		SR-BI	–	–	–	0.14	0.48	250
SPT	HepG2	CD81	0.11	0.11	3000	0.17	0.16	3000	***
		CD81ΔC	0.10	0.13	2000	0.10	0.13	2000
		HCVpp on HepG2.CD81	0.07	0.21	1500	0.14	0.25	1500	***
		HCVpp on HepG2.CD81ΔC	0.05	0.14	1500	0.09	0.30	1500

^an, number of events measured.

^bComparison of median DC in polarized and non-polarized cells (Mann–Whitney test, ***P ≤ 0.001).