Table 5.
Inflammation and cytotoxicity in 24 h for the different doses
|
Study dose (mg/ml) |
Inflammationa (h) |
|
Cytotoxicity at 24 ha (nm) |
|
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ≤24 | ≤48 | Total | Percentageb | <10 | 10 to 20 | 21 to 40 | 40 to 100 | Total | Percentageb | |
| ≤0.005 |
0/1 |
0/2 |
0/3 |
0 |
0/2 |
1/6 |
0/3 |
0/2 |
1/13 |
/7 |
| ≤0.05 |
0/1 |
0/2 |
0/3 |
0 |
0/3 |
7/3 |
4/2 |
0/2 |
11/10 |
52 |
| ≤0.5 |
1/1 |
1/1 |
2/2 |
50 |
2/2/ |
5/2 |
5/2 |
0/2 |
12/8 |
60 |
| ≤5 |
0/0 |
1/1 |
1/1 |
50 |
0/0 |
3/1 |
1/1 |
1/0 |
5/2 |
71 |
| Total |
1/3 |
2/6 |
3/9 |
- |
2/7 |
16/12 |
10/8 |
1/6 |
29/33 |
47 |
| Percentageb | 25 | 25 | 25 | - | 22 | 57 | 56 | 14 | - | - |
aNumber of positive/negative studies.
bPercentage of positive studies.