Table 3.
Respiratory symptom |
Total population |
Males |
Females |
|||
---|---|---|---|---|---|---|
|
OR (95% CI) of atopy |
OR (95% CI) of atopy |
OR (95% CI) of atopy |
|||
Placebo | Budesonide | Placebo | Budesonide | Placebo | Budesonide | |
Wheezing at any time |
1.15 (0.71–1.87) |
0.79 (0.45–1.43) |
1.24 (0.74–2.08) |
0.92 (0.48–1.75) |
0.64 (0.15–2.78) |
0.43 (0.10–1.85) |
Cough day/night or a.m. |
1.79 (1.03–3.08)* |
0.83 (0.42–1.62) |
1.69 (0.93–3.08)# |
0.84 (0.38–1.84) |
2.52 (0.64–9.86) |
0.60 (0.17–2.08) |
Phlegm day/night or a.m. |
1.50 (0.84–2.69) |
0.91 (0.54–1.53) |
1.55 (0.82–2.93) |
0.85 (0.46–1.59) |
1.30 (0.36–4.67) |
0.92 (0.38–2.27) |
Trouble with breathing |
1.12 (0.66–1.89) |
0.68 (0.37–1.24) |
1.09 (0.59–1.99) |
0.79 (0.42–1.51) |
1.23 (0.44–3.44) |
0.22 (0.4–1.13)# |
Woken with chest tightness |
1.33 (0.74–2.38) |
1.07 (0.57–1.99) |
1.35 (0.69–2.65) |
1.08 (0.55–2.12) |
1.08 (0.27–4.34) |
1.11 (0.23–5.39) |
Attack of dyspnea after activity | 0.98 (0.59–1.62) | 1.49 (0.88–2.51) | 0.76 (0.43–1.33) | 1.55 (0.88–2.73)$ | 2.79 (0.94–8.31)# | 0.89 (0.22–3.62) |
*OR is significant at p < 0.05. Each model was adjusted for sex, age, BMI, pack years of smoking, number of cigarettes and FEV1 % pred.
#Trend (0.05 < p. value < 0.1).
$Interaction between Phadiatop and treatment group has a p.value < 0.05.