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Defective ciliary targeting of MCHR1 in the neuronal cilia of the tubby mutant. MCHR1 (red) is found in neuronal cilia in WT (upper panels) but is lost from cilia in the mutant (lower panels) in both hippocampus (A) and in the hypothalamus (B). Rootletin staining (green) serves as a marker for the ciliary base. Cell nuclei were stained (blue) with DAPI.
