Figure 1.

Columnar scatter plot of the quantitative expression of COL11A1 in cartilage cDNA stratified by genotype at A) the OA associated SNP rs2615977 and B) the LDH associated SNP rs1676486. Due to the low frequency of TT homozygotes at rs1676486 the analysis in B) was between CC homozygotes and T-allele carriers (CT and TT combined) at this SNP. n is the number of patients studied for each group. The horizontal lines in each plot represent the mean and the standard error of the mean. P-values were calculated using a Kruskal-Wallis test for A) and a Mann–Whitney U test for B).